Edit |   |
---|---|
Antigenic Specificity | RAG2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin co |
Immunogen | Immunogen: Recombinant protein of human RAG2 (NP 001230715.1). |
Other Names | [V(D)J recombination-activating protein 2; V(D)J recombination-activating protein 2; V(D)J recombination-activating protein 2; recombination activating 2] |
Gene, Accession # | [RAG2], Gene ID: 5897, NCBI: NP_000527.2, UniProt: P55895 |
Catalog # | MBS8567354 |
Price | $280 |
Order / More Info | RAG2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |