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Antigenic Specificity | Human PRKCA / PKC-Alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg |
Concentration | 0.1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Amino acids 491 to 501 with pTHR497 of human PRKCA. Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in positive and negative regulation of cell proliferation, apoptosis, differentiation, migration and adhesion, tumorigenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation, by directly phosphorylating targets such as RAF1, BCL2, CSPG4, TNNT2/CTNT, or activating signaling cascade involving MAPK1/3 (ERK1/2) and RAP1GAP. Involved in cell proliferation and cell growth arrest by positive and negative regulation of the cell cycle. Can promote cell growth by phosphorylating and activating RAF1, which mediates the activation of the MAPK/ERK signa |
Immunogen | Immunogen Description: Synthetic peptide from human PRKCA / PKC-Alpha. |
Other Names | [PRKCA / PKC-Alpha (phospho-Thr497) IHC-plus; PRKCA; Aging-associated gene 6; AAG6; Alpha PKC; PKC-A; Pkcalpha; Protein kinase C alpha type; PKC Alpha; PKC-alpha; PKCA; Protein kinase c alpha; Protein kinase C; alpha; Human PRKCA; PKC-Alpha], [PRKCA; PRKCA; AAG6; PKCA; PRKACA; PKC-alpha; PKCA; PRKACA; PKC-A; PKC-alpha] |
Gene, Accession # | [PRKCA], Gene ID: 5578, NCBI: NP_002728.1, UniProt: P17252 |
Catalog # | MBS241041 |
Price | $530 |
Order / More Info | Human PRKCA / PKC-Alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |