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Antigenic Specificity | Human Factor VIII |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is specific for F.VIII as demonstrated by immunoelectrophoresis and ELISA. Factor VIII (formerly referred to as antihemophilic globulin and Factor VIII:C) is a large glycoprotein (320 kDa) that circulates in plasma at approximately 200 ng/ml. Synthesized in the liver, the majority of Factor VIII is cleaved during expression, resulting in a heterogeneous mixture of partially cleaved forms of F.VIII ranging in size from 200-280 kDa. The F.VIII is stabilized by association with von Willebrand Factor to form a F.VIII-vWF complex required for the normal survival of F.VIII in vivo (t1/2 of 8-12 hours). F.VIII is a pro-cofactor that is activated through limited proteolysis by thrombin. In this process F.VIIIa dissociates from vWF to |
Immunogen | Immunogen: Human F.VIII (F.VIII:C) purified from concentrate. |
Other Names | [factor VIII; coagulation factor VIII; coagulation factor VIII] |
Gene, Accession # | Gene ID: 2157 |
Catalog # | MBS4157089 |
Price | $585 |
Order / More Info | Human Factor VIII Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |