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Antigenic Specificity | NM23 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NM23 antibody detects endogenous levels of total NM23. Description: NM23 nucleoside diphosphate kinase A. Major role in the synthesis of nucleoside triphosphates other than ATP. Holoenzyme is a hexamer of the A and B subunits. Mutations have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been described.Function: Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.Subunit Structure: Hexamer of two different chains: A and B (A6, A5B, A4B2, A3B3 |
Immunogen | Immunogen: A synthesized peptide derived from human NM23 Subcellular Location: Cytoplasm. Nucleus. Isoform 2 is mainly cytoplasmic and isoform 1 and isoform 2 are excluded from the nucleolus. Tissue Specificity: Isoform 1 and isoform 3 are ubiquitously expressed. Predicted Cross Reactivity: Pig, Bovine, Rabbit, Dog Similarity: Pig (100%), Bovine (93%), Rabbit (100%), Dog (100%) |
Other Names | [C myc purine binding transcription factor PUF; C myc transcription factor; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; MGC111212; MGC2212; NDK B; NDKB; NDKB_HUMAN; NDP kinase B; NDPK B; NDPKB; NM23 H2; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Non metastatic cells 2, protein (NM23B) expressed in; non-metastatic cells 2, protein (NM23) expressed in; Nucleoside diphosphate kinase B; Nucleotide diphosphate kinase B; PUF] |
Gene, Accession # | [NM23], Gene ID: 654364, NCBI: NP_001018146.1, UniProt: P22392 |
Catalog # | MBS9600159 |
Price | $240, $280 |
Order / More Info | NM23 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |