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Antigenic Specificity | Gli1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. |
Immunogen | Immunogen: A synthesized peptide derived from human Gli1. Subcellular Localization: Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1. Tissue Specificity: Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve |
Other Names | [Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; GLI1; GLI], [GLI1; GLI1; GLI; GLI] |
Gene, Accession # | [Gli1], Gene ID: 2735, NCBI: NP_001153517.1, UniProt: P08151 |
Catalog # | MBS179353 |
Price | $160, $340, $340 |
Order / More Info | Gli1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |