TRIO Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TRIO |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Triple functional domain protein(TRIO) detection. Tested with WB in Human;Mouse;Rat. Background: Triple functional domain protein is a protein that in humans is encoded by the TRIO gene. This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Additionally, the TRIO protein contains 3 functional domains: a serine/threonine kinase domain and 2 guanine nucleotide exchange factor (GEF) domains for the family of Rho-like GTPases, specific for Rac1 and RhoA, respectively. These domains suggest that this enzyme may play a key role in several signaling path |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRIO (787-830aa QLRIFERDAIDIISDLESWNDELSQQMNDFDTEDLTIAEQRLQH), identical to the related mouse and rat sequences. Ig Type: Rabbit IgG |
| Other Names | [Triple functional domain protein; ARHGEF23; PTPRF-interacting protein; tgat; trio; TRIO_HUMAN; Triple functional domain protein; trio Rho guanine nucleotide exchange factor], [TRIO; TRIO; tgat; ARHGEF23] |
| Gene, Accession # | [TRIO], Gene ID: 7204, NCBI: NP_009049.2, UniProt: O75962 |
| Catalog # | MBS177816 |
| Price | $280 |
| Order / More Info | TRIO Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: TRIO triple functional domain (PTPRF interacting). 2. Debant, A., Serra-Pages, C., Seipel, K., O'Brien, S., Tang, M., Park, S.-H., Streuli, M. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. Proc. Nat. Acad. Sci. 93: 5466-5471, 1996. 3. Taviaux, S., Diriong, S., Bellanger, J.-M., Streuli, M., Debant, A. Assignment of TRIO, the trio gene (PTPRF interacting) to human chromosome bands 5p15.1-p14 by in situ hybridization. Cytogenet. Cell Genet. 76: 107-108, 1997. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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