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Antigenic Specificity | Phospho-AhR (Ser36) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-AhR (Ser36) antibody detects endogenous levels of AhR only when phosphorylated at Serine 36. Description: The Aryl Hydrocarbon Receptor (AHR), also known as the dioxin receptor, is a ligand-activated helix/loop/helix transcription factor found in a variety of vertebrate species. The known ligands for AHR are foreign planar aromatic compounds, such as polycyclic aromatic compounds and halogenated aromatic compounds such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD).Function: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemic |
Immunogen | Immunogen: A synthesized peptide derived from human AhR around the phosphorylation site of Serine 36 Subcellular Location: Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. Tissue Specificity: Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100 |
Other Names | [Ah receptor; AhR; AHR_HUMAN; Aromatic hydrocarbon receptor; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; bHLHe76; Class E basic helix loop helix protein 76; Class E basic helix-loop-helix protein 76; HGNC:348; AHH; AhR repressor; AhRR; AHRR_HUMAN; aryl hydrocarbon hydroxylase regulator; aryl hydrocarbon receptor regulator; Aryl hydrocarbon receptor repressor; Arylhydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; Dioxin receptor repressor; KIAA1234; MGC167813; MGC176630; OTTHUMP00000221488; OTTHUMP00000221489] |
Gene, Accession # | [AhR], Gene ID: 196, NCBI: NP_001612.1, UniProt: P35869 |
Catalog # | MBS9601049 |
Price | $240, $280 |
Order / More Info | Phospho-AhR (Ser36) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |