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Antigenic Specificity | TMPRSS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-400 of human TMPRSS2 (NP 001128571.1). |
Other Names | [PP9284; PRSS10] |
Gene, Accession # | [TMPRSS2], Gene ID: 7113, NCBI: NP_001128571.1, UniProt: O15393 |
Catalog # | MBS8544715 |
Price | $280 |
Order / More Info | TMPRSS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |