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Antigenic Specificity | IL-16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody will only detect the NIL-16 isoform. IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediat |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 14 amino acid peptide near the amino terminus of human IL-16. |
Other Names | [Interleukin 16, leukocyte chemoattractant factor, LCF, NIL-16] |
Gene, Accession # | [IL-16], NCBI: AAQ86961 |
Catalog # | MBS9402455 |
Price | $320 |
Order / More Info | IL-16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |