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Antigenic Specificity | RhoGDI |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of RhoGDI in human samples. Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them; and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42; RAC1 and RHOA in an inactive cytosolic pool; regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell; mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins; may play a role in cell motility regulation. In glioma cells; inhibits cell m |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RhoGDI alpha |
Other Names | [GDIA1; Rho GDP-dissociation inhibitor 1; Rho GDI 1; Rho-GDI], [ARHGDIA] |
Gene, Accession # | [RhoGDI], Gene ID: 396, NCBI: NP_001172006.1, UniProt: P52565 |
Catalog # | MBS846039 |
Price | $345 |
Order / More Info | RhoGDI Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |