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Antigenic Specificity | SLIT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for SLIT1 detection. Tested with WB in Human; Mouse; Rat.Background: Slit homolog 1 protein is a protein that in humans is encoded by the SLIT1 gene. This gene is mapped to 10q24.1. Members of the SLIT family, such as SLIT1, are secreted glycoproteins that bind and activate ROBO receptors and function in axon guidance during development. It is suggested that Slit may provide a molecular tool with potential therapeutic applications in controlling and directing cell migration. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human SLIT1 (ECEKLLSVNFVDRDTYLQFTDLQNWPRA). |
Other Names | [Slit homolog 1 protein; Slit-1; Multiple epidermal growth factor-like domains protein 4; Multiple EGF-like domains protein 4; SLIT1; KIAA0813; MEGF4; SLIL1; Slit guidance ligand 1] |
Gene, Accession # | [SLIT1], Gene ID: 6585, NCBI: NP_003052.2, UniProt: O75093 |
Catalog # | MBS1751467 |
Price | $280 |
Order / More Info | SLIT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Bagri, A., Marin, O., Plump, A. S., Mak, J., Pleasure, S. J., Rubenstein, J. L. R., Tessier-Lavigne, M. Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron 33: 233-248, 2002. 2. Hochstim, C., Deneen, B., Lukaszewicz, A., Zhou, Q., Anderson, D. J. Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell 133: 510-522, 2008. 3. Itoh, A., Miyabayashi, T., Ohno, M., Sakano, S. Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system. Molec. Brain Res. 62: 175-186, 1998. |