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Antigenic Specificity | Ephrin Receptor A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Ephrin type-A receptor 1 Antibody. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 55-605 on human Ephrin type-A receptor 1. Immunoglobulin: IgG. Expression: Overexpressed in several carcinomas. |
Other Names | [EPH; EPH receptor A1; Eph tyrosine kinase 1; EphA1; Ephrin receptor Eph A1; Ephrin type-A receptor 1; EPHT 1; Erythropoietin producing hepatoma amplified sequence; Esk; Esk; hEpha1; MGC163163; Oncogene EPH; Soluble EPHA1 variant 1; Soluble EPHA1 variant 2; Tyrosine protein kinase receptor EPH], [EPHA1; EPHA1; EPH; EPHT; EPHT1; EPH; EPHT; EPHT1; hEpha1] |
Gene, Accession # | Gene ID: 2041, NCBI: P21709.4, UniProt: P21709 |
Catalog # | MBS541513 |
Price | $390 |
Order / More Info | Ephrin Receptor A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |