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Antigenic Specificity | CREST |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SS18-like 1 (SS18L1) is a transcriptional activator that is required for calcium-dependent dendritic growth and branching in cortical neurons. It's also a nuclear protein interacts with CREB-binding protein and expressed in the developing brain. It helps regulate neuronal morphogenesis in calcuim-dependent manner. The N-terminal domain of SS18L1 is required for suppressing transactivation in the basal state, while the C-terminal domain is required for calcium-induced transactivation. It's part of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. This complex also binds to the NR2B promoter, and activ |
Immunogen | Immunogen: CREST fusion protein ag3119 |
Other Names | [CREST; KIAA0693; LP2261; SS18 like protein 1; SS18L1; SYT homolog 1] |
Gene, Accession # | [CREST], Gene ID: 26039, NCBI: NP_001288707.1, UniProt: O75177 |
Catalog # | MBS2540181 |
Price | $220, $290, $435 |
Order / More Info | CREST Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |