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Antigenic Specificity | Human occludin |
Clone | polyclonal |
Host Species | Guinea Pig |
Reactive Species | reactivity: human. cross reactivity: dog, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Product Description: The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-char |
Immunogen | n/a |
Other Names | [occludin; Occludin; occludin], [OCLN; OCLN] |
Gene, Accession # | Gene ID: 403844, NCBI: NP_001003195.1 |
Catalog # | MBS584484 |
Price | $520 |
Order / More Info | Human occludin Antibody from MYBIOSOURCE INC. |
Product Specific References | Van Itallie, C et al; Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 1997, 110: 1113. |