Edit |   |
---|---|
Antigenic Specificity | Calregulin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Calregulin Polyclonal Antibody detects endogenous levels of Calregulin protein. Calreticulin is a multifunctional protein that acts as a major Ca (2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind ca |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Calregulin at AA range: 40-120 |
Other Names | [Rabbit Calregulin; CRTC; Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60] |
Gene, Accession # | [CALR], Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS9701563 |
Price | $130, $220, $325 |
Order / More Info | Calregulin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |