Pyruvate Kinase (PKM2) (C-term), 476-505 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Pyruvate Kinase (PKM2) (C-term), 476-505 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, monkey |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2). There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. |
| Immunogen | n/a |
| Other Names | [Pyruvate kinase PKM; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58; PKM; OIP3; PK2; PK3; PKM2] |
| Gene, Accession # | [PKM], Gene ID: 5315, NCBI: NP_001193725.1, UniProt: P14618 |
| Catalog # | MBS9206786 |
| Price | $165, $370 |
| Order / More Info | Pyruvate Kinase (PKM2) (C-term), 476-505 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Williams, J.M., et al., Mol. Microbiol. 27(1):171-186 (1998). 2.Gress, T.M., et al., Oncogene 13(8):1819-1830 (1996). 3.Kato, H., et al., Proc. Natl. Acad. Sci. U.S.A. 86(20):7861-7865 (1989). 4.Tsutsumi, H., et al., Genomics 2(1):86-89 (1988). 5.Tani, K., et al., Gene 73(2):509-516 (1988). References for MCF7 cell line: 1.Soule, HD; Vazquez J; Long A; Albert S; Brennan M. (1973). A human cell line from a pleural effusion derived from a breast carcinoma. Journal of the National Cancer Institute 51 (5): 1409-1416. [PMID 4357757]. 2.Levenson, AS; Jordan VC. (1997). MCF-7: the first hormone-responsive breast cancer cell line. Cancer Research 57 (15): 3071-3078. [PMID 9242427]. 3.Lacroix, M; Leclercq G. (2004). Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Research and Treatment 83 (3): 249-289.[PMID 14758095]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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