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Antigenic Specificity | PAR-2 |
Clone | [3G233] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes native peptide and the N-terminus of the human PAR-2. Does not crossreact with PAR-1. Serine proteases comprise a large family of enzymes that are characterized by a uniquely reactive Ser side chain. They are ubiquitous in prokaryotes and eukaryotes and serve important and diverse biological functions. Although serine proteases are usually considered to act principally as degradative enzymes, certain proteases are signaling molecules that specifically regulate cells by cleaving and triggering members of a new family of Proteinase Activated Receptors (PARs). There are three members of this family, PAR-1 and PAR-3, which are receptors for thrombin, and PAR-2, a receptor for trypsin and mast cell tryptase. Proteases cleave within th |
Immunogen | Immunogen: Synthetic peptide corresponding to the N-terminal of the human PAR-2 receptor. |
Other Names | PAR-2 (Proteinase-activated receptor 2, F2RL1, Coagulation Factor II (thrombin) receptor-like 1, Coagulation Factor II receptor-like 1, GPR11, G-protein coupled receptor 11, PAR2, Thrombin receptor-like 1) |
Gene, Accession # | Gene ID: 2150, NCBI: NP_005233.3, UniProt: P55085 |
Catalog # | MBS601311 |
Price | $635 |
Order / More Info | PAR-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |