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Antigenic Specificity | Phospho-Histone H2A.X (Ser139) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Histone H2A.X (Ser139) antibody detects endogenous levels of Histone H2A.X only when phosphorylated at Serine 139. Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, |
Immunogen | Immunogen: A synthesized peptide derived from human Histone H2A.X around the phosphorylation site of Serine 139 Subcellular Location: Nucleus. Chromosome. Tissue Specificity: Synthesized in G1 as well as in S-phase. Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (91%), Sheep (91%), Dog (91%) |
Other Names | [AW228881; H2A histone family member X; H2A.FX; H2A.X; H2a/x; H2AFX; H2AX; H2AX histone; H2AX_HUMAN; Hist5.2ax; Histone 2A; Histone 2AX; Histone H2A.X; Histone H2AX; RGD1566119] |
Gene, Accession # | [H2AFX], Gene ID: 3014, NCBI: NP_002096.1, UniProt: P16104 |
Catalog # | MBS9600958 |
Price | $240, $280 |
Order / More Info | Phospho-Histone H2A.X (Ser139) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |