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Antigenic Specificity | Trk C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Trk C Polyclonal Antibody detects endogenous levels of Trk C protein. NTRK3 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Trk C |
Other Names | [Rabbit Trk C; NTRK3; NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase] |
Gene, Accession # | [TRKC], Gene ID: 4916, NCBI: NP_001012338.1, UniProt: Q16288 |
Catalog # | MBS9703556 |
Price | $130, $220, $325 |
Order / More Info | Trk C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |