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Antigenic Specificity | Toll-like Receptor 7 |
Clone | [3F11-2C9-D8] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 3.07mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS respo |
Immunogen | Immunogen: Purified recombinant human Toll-like Receptor protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Toll-like Receptor and does not cross-react with related proteins. Sequence Similarities: Belongs to the Toll-like receptor family. Contains 27 LRR (leucine-rich) repeats. Contains 1 TIR domain. |
Other Names | [PRO285; TLR 7; Tlr7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248], [TLR7-like] |
Gene, Accession # | [TLR7], Gene ID: 51284, NCBI: NP_057646.1, UniProt: Q9NYK1 |
Catalog # | MBS475314 |
Price | $335 |
Order / More Info | Toll-like Receptor 7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |