Edit |   |
---|---|
Antigenic Specificity | Netrin 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Netrin 1 is a diffusible protein made by floor plate cells. Netrin 1 is found in the floor plate and neuroepithelial cells of the ventral region of the spinal cord, as well as other locations in the nervous system including the somatic mesoderm, pancreas and cardiac muscle. The human NTN1 gene is mapped to chromosome 17p13-p12 by FISH. Netrin 1 can attract spinal commissural axons and repel trochlear axons in vitro. And Netrin 1 expression confers a selective advantage for tumor cell survival. The binding of Netrin 1 to DCC appears to depend on the presence of a coreceptor or accessory proteins. Adenosine A2b receptor is actually a Netrin 1 receptor and induces cAMP accumulation on binding Netrin 1, and that Netrin 1-dependent outgrowth of |
Immunogen | Immunogen: Netrin 1 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Netrin 1, identical to the related rat and Rabbit sequences, as the immunogen |
Other Names | [Affinity Purified Rabbit Netrin 1; Netrin 1; Netrin 1; NTN1L; Netrin 1; Netrin 1; Netrin 1; Netrin -1; Netrin -1; NTN1] |
Gene, Accession # | [NTN1] |
Catalog # | MBS5312958 |
Price | $345 |
Order / More Info | Netrin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |