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Antigenic Specificity | NKCC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | reacts with: human, rat. predicted to work with: mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Frozen Section. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Solute carrier family 12(sodium/potassium/chloride transporters), member 2, also known as NKCC1, is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ hybridization, this gene is mapped to chromosome 5q23.3. The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC12A2 (223-241aa RIDHYRHTAAQLGEKLLRP), identical to the related mouse and rat sequences. |
Other Names | [Solute carrier family 12 member 2; solute carrier family 12(sodium/potassium/chloride transporters), member 2; Basolateral Na-K-Cl symporter; BSC; BSC2; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; mBSC2; MGC104233; NKCC1; S12A2_HUMAN; SLC12A2; sodium-potassium-chloride cotransporter 1; solute carrier family 12(sodium/potassium/chloride transporters) member 2; Solute carrier family 12 member 2; sy-ns], [SLC12A2; SLC12A2; BSC; BSC2; NKCC1; PPP1R141; NKCC1] |
Gene, Accession # | [SLC12A2], Gene ID: 6558, NCBI: P55011.1, UniProt: P55011 |
Catalog # | MBS176766 |
Price | $315 |
Order / More Info | NKCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |