HLA-DRB (MHC II) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HLA-DRB (MHC II) |
| Clone | [Bra30] |
| Host Species | Mouse |
| Reactive Species | human, baboon, chimpanzee, monkey, squirrel, dog |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. |
| Immunogen | Immunogen: Human REH cells (non-T, non-B leukemia cell line) |
| Other Names | [HLA class II histocompatibility antigen DR beta 3 chain; HLADR3B; Major histocompatibility complex; class II DR beta 3] |
| Gene, Accession # | [HLA-DRB], Gene ID: 3123, NCBI: NP_002115.2, UniProt: P01911 |
| Catalog # | MBS4380981 |
| Price | $190, $340, $340 |
| Order / More Info | HLA-DRB (MHC II) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Cresswell, P., 1996. Cell 84. 505-507. 2. Barclay, A.N., et al., eds. 1997. The Leucocyte Antigen Facts Book. Academic Press. London. 3. Seddon, B., and Mason, D., 1996. Int. Immunol. 8. 1185-119 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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