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Antigenic Specificity | Human CD154 (CD40L) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD154/CD40 Ligand. CD154, also known as CD40 ligand and a member of the tumor necrosis factor superfamily of cell surface receptors, is a 33 kDa type II transmembrane protein that is expressed as a trimer on the cell surface. It is absent from resting lymphocytes but its expression is rapidly upregulated upon activation. It is present mostly on CD4+ cells but also on a small subpopulation of CD8+ cells and gamma delta+ T cells. It is also found on activated basophils and mast cells. CD154 binding to CD40 on B lymphocytes is required for secondary immune responses and germinal center formation. This interaction may also play a role in negative selection and peripheral tolerance. |
Immunogen | n/a |
Other Names | [CD154-CD40L] |
Gene, Accession # | [CD154] |
Catalog # | MBS4152233 |
Price | $445 |
Order / More Info | Human CD154 (CD40L) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |