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Antigenic Specificity | IL-8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein G purified |
Size | 0.1 mg, 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB), IHC (Immunohistochemistry), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL8 is produced by stimulated monocytes but not by tissue macrophages and T- lymphocytes. In many cell types the synthesis of IL8 is strongly stimulated by IL1 and TNF- alpha. In human skin fibroblasts the expression of IL-8 is enhanced by Leukoregulin.The expression of IL-8 from resting and stimulated human blood monocytes is up-regulated by IL-7. In chondrocytes the synthesis of IL8 is stimulated by IL1-beta TNF- alpha and bacterial lipopolysaccharides. In human astrocytes the synthesis and secretion of IL8 is induced by IL-1 and TNF-alpha. The IL8 receptor is a dimeric glycoprotein consisting of a 59 kDa and a 67 kDa subunit. It has been given the name CD128. It is expressed in many different cell types including those not responding to |
Immunogen | Host Note: Polyclonal Interleukin-8 antibody was produced from sera of rabbits immunized with synthetic protein containing Interleukin-8 antigenic determinants. Dilution: A quick spin of the vial followed by reconstitution in 0.01M PBS pH 7.4 or other diluents. |
Other Names | [Rabbit IL-8 purified; il-8; il8; NAP-1; nap1; cxcl8; pab;], [IL8; CXCL8; IL-8; GCP-1; MDNCF; MONAP; NAP-1; LYNAP; NAF] |
Gene, Accession # | [IL-8], Gene ID: 3576, NCBI: NP_000575.1, UniProt: P10145 |
Catalog # | MBS551025 |
Price | $280, $385 |
Order / More Info | IL-8 Antibody from MYBIOSOURCE INC. |
Product Specific References | • cell surface-bound il-1 is an upstream regulator of the senescence-associated il-6/IL-8 cytokine network.PNAS, Sep 2009; 10.1073/pnas.0905299106. • the angiogenic effect of probiotic bacillus polyfermenticus on human intestinal microvascular endothelial cells is mediated by IL-8.Am J Physiol Gastrointest Liver Physiol, Sep 2009; 10.1152/ajpgi.00204.2009. • IL-8 signaling does not mediate intra-amniotic lps-induced inflammation and maturation in preterm fetal lamb lung.Am J Physiol Lung Cell Mol Physiol, Sep 2009; 297: L512 - L519. • the functional significance behind expressing two IL-8 receptor types on pmn.J. Leukoc. Biol., Sep 2009; 86: 529 - 543. • IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.J. Immunol., Aug 2009; 183: 2159 - 2166. |