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Antigenic Specificity | AMOTL2 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene. Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). It mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. Protein Function: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recyc |
Immunogen | Immunogen: E Coli-derived human AMOTL2 recombinant protein (Position: A401-Q480). Subcellular Localization: Recycling endosome. |
Other Names | [Angiomotin-like protein 2; Leman coiled-coil protein; LCCP; AMOTL2; KIAA0989] |
Gene, Accession # | [AMOTL2], Gene ID: 51421, NCBI: NP_001265612.1, UniProt: Q9Y2J4 |
Catalog # | MBS1750915 |
Price | $280 |
Order / More Info | AMOTL2 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |