Edit |   |
---|---|
Antigenic Specificity | Human IL32 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines, and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma and delta) are the most representative IL-32 transcripts, and gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-3 |
Immunogen | Immunogen: Recombinant Human IL32 Protein Buffer: 0.2 mum filtered solution in PBS |
Other Names | [interleukin-32 isoform B; Interleukin-32; interleukin-32; interleukin 32; Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor] |
Gene, Accession # | [IL32 ], Gene ID: 9235 |
Catalog # | MBS2544160 |
Price | $215, $330, $500 |
Order / More Info | Human IL32 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |