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Antigenic Specificity | OPTN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using OPTN antibody. Immunohistochemistry of paraffin-embedded human esophageal cancer using OPTN antibody at dilution of 1:100 (200x lens). Immunohistochemistry of paraffin-embedded rat kidney using OPTN antibody at dilution of 1:100 (200x lens). This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle tr |
Immunogen | Immunogen: Recombinant protein of human OPTN |
Other Names | [optineurin; Optineurin; optineurin; optineurin; E3-14.7K-interacting protein; FIP-2; Huntingtin yeast partner L; Huntingtin-interacting protein 7; HIP-7; Huntingtin-interacting protein L; NEMO-related protein; Optic neuropathy-inducing protein; Transcription factor IIIA-interacting protein; TFIIIA-IntP], [OPTN; OPTN; NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP; FIP2; GLC1E; HIP7; HYPL; NRP; HIP-7; TFIIIA-IntP] |
Gene, Accession # | [OPTN], Gene ID: 10133, NCBI: NP_001008214.1, UniProt: Q96CV9 |
Catalog # | MBS419850 |
Price | $385 |
Order / More Info | OPTN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |