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Antigenic Specificity | WDR82 (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This WDR82 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12~46 amino acids from the N-terminal region of human WDR82. Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. |
Immunogen | n/a |
Other Names | [WD repeat-containing protein 82; Protein TMEM113; Swd2; WDR82; TMEM113; WDR82A] |
Gene, Accession # | [WDR82], Gene ID: 80335, NCBI: NP_079498.2, UniProt: Q6UXN9 |
Catalog # | MBS9204761 |
Price | $165, $370 |
Order / More Info | WDR82 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Clark H.F.,et al.Genome Res. 13:2265-2270(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Lee J.-H.,et al.J. Biol. Chem. 280:41725-41731(2005). Higa L.A.,et al.Nat. Cell Biol. 8:1277-1283(2006). |