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Antigenic Specificity | URACIL-DNA GLYCOSYLASE 1 (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises uracil-DNA glycosylase 1 (UNG1), a member of the uracil-DNA glycosylase and cyclin family. Two isoforms of UNG exist, isoform 1 is expressed in the mitochondria of in skeletal muscle, heart and testicles while isoform 2 (UNG2) is more abundant in proliferating tissues and expressed in the nucleus.. . Uracil residues can be misincorporated into DNA by DNA polymerase or by deamination of cytosine. UNG1 is a major enzyme in base excision repair, excising the misincorporated uracil residues in a process crucial to increasing immunoglobulin diversity. In association with activation-induced cytosine deaminase, UNG is also essential to the generation of strand breaks that initiate class switch recombination.. . UNG is also |
Immunogen | Immunogen: 14 amino acid peptide sequence near the amino terminus of human UNG1. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human uracil-DNA glycosylase 1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [uracil-DNA glycosylase isoform UNG1; Uracil-DNA glycosylase; uracil-DNA glycosylase; UDG; UNG; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; uracil-DNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15;] |
Gene, Accession # | Gene ID: 7374, NCBI: NP_003353.1, UniProt: P13051 |
Catalog # | MBS221489 |
Price | $375 |
Order / More Info | URACIL-DNA GLYCOSYLASE 1 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |