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Antigenic Specificity | TrkB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.2 mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting thromugh trkB such as BDNF. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 810 of human TrkB |
Other Names | [NTRK2; GP145-TrkB; TRKB; Trk-B; tyrosine receptor kinase], [Ntrk2; Ntrk2; Tkrb; trkB; TRKB1; trk-B; RATTRKB1; Trkb; Trk-B] |
Gene, Accession # | [TrkB], Gene ID: 25054, NCBI: NP_001156640.1, UniProt: Q63604 |
Catalog # | MBS840689 |
Price | $150, $360 |
Order / More Info | TrkB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |