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Antigenic Specificity | Phospho-EIF4A1 (Tyr48) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-EIF4A1(Tyr48) Antibody detects endogenous levels of EIF4A1 only when phosphorylated at Tyr48. Description: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.Subunit Structure: eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. Interacts with PAIP1, EIF4E and UPF2. Fo |
Immunogen | Immunogen: A synthesized peptide derived from human EIF4A1 around the phosphorylation site of Tyr48. |
Other Names | [ATP-dependent RNA helicase eIF4A-1; DDX2; DDX2A; eIF 4A I; eIF-4A-I; EIF4A; eIF4A I; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4AI; eukaryotic translation initiation factor 4A, isoform 1; Eukaryotic translation initiation factor 4A1; IF4A1_HUMAN] |
Gene, Accession # | [EIF4A1], Gene ID: 1973, NCBI: NP_001407, UniProt: P60842 |
Catalog # | MBS9610416 |
Price | $225, $280, $340 |
Order / More Info | Phospho-EIF4A1 (Tyr48) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |