CD14 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD14
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD14. CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.
Immunogenn/a
Other Names[monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14; monocyte differentiation antigen CD14; CD14 molecule; Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14], [CD14; CD14]
Gene, Accession #[CD14], Gene ID: 929, NCBI: NP_000582.1, UniProt: P08571
Catalog #MBS859660
Price$280
Order / More InfoCD14 Antibody from MYBIOSOURCE INC.
Product Specific References1. Crystal structure of CD14 and its implications for lipopolysaccharide signaling.Kim J.I., Lee C.J., Jin M.S., Lee C.H., Paik S.G., Lee H., Lee J.O.J. Biol. Chem. 280:11347 11351(2005). The phagosomal proteome in interferon-gamma-activated macrophages.Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.Immunity 30:143 154(2009).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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