Human LTbetaR Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human LTbetaR |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human Lymphotoxin beta receptor (LTbetaR, TNFRSF3) is a member of the TNF receptor superfamily with similarilty to CD120a(TNFR1) and CD120b(TNFR2). It is a expressed mainly on non lymphoid tissues(1) and appears to have an important role in secondary lymphoid organ development(5). Suppression of LTbetaR signaling can alleviate autoimmunity(2) or exasperate mycobacterial infection(6). Its ligands include Ltab2 and LIGHT. In mice, LTbetaR signaling is important for development and function of HEV(2), Dendritic cells(3), and Mast cells(4). Antibody ANCLTR2 binds to human LTbetaR present on U-937 cell surface, and to recombinant LTbetaR-muIg in EIA. |
| Immunogen | Immunogen: Recombinant Human LT |
| Other Names | [human LTbR (Lymphotoxin beta receptor)/Biotin], [Ltbr; Ltbr; CD18; Ltar; TNFCR; Tnfbr; TNFRrp; LTbetaR; TNFR-RP; Tnfrsf3; AI256028; TNFR2-RP; TNF-R-III; Tnfcr; Tnfrsf3] |
| Gene, Accession # | Gene ID: 17000, NCBI: AAI38592.1 |
| Catalog # | MBS666776 |
| Price | $440 |
| Order / More Info | Human LTbetaR Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) T W Mak, M E Saunders eds. The Immune Response 2006 Elsevier Academic Press p 499.2) J L Browning, R.A. Fava, et al. Immunity (2005) 23(5): 539-50. 3)Y Wang, Y Fu, et al. J Immunol (2005) 175: 6997-7002. 4) P Stopfer, T Hehlgans, et al. J Immunol (2004) 172: 7459-7465. 5) Gommermann J, JL Browning, et al, Nat Rev Immunol (2003) 3:642-655. 6) Spahn TW, T Kucharzik, et al. Infection and Immunity (2005) 73(11): 7077-7088. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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