Tyrosine Kinase Receptor B (TrkB, 23-36) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTyrosine Kinase Receptor B (TrkB, 23-36)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentration1ug/ul
ApplicationsImmunohistochemistry (IHC)
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DescriptionSpecificity: Sequence was chosen to avoid cross reactivity with TrkA and TrkC. FUNCTION: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures (By similarity). Binds APS. Interacts with SQSTM1. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. ALTERNATIVE produc
ImmunogenImmunogen: A synthetic peptide (AFPRLEPNSIDPENC) as part of rat mature TrkB protein (aa: 23-36) conjugated to KLH. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide.
Other Names[trkB; BDNF/NT-3 growth factors receptor; BDNF/NT-3 growth factors receptor; neurotrophic receptor tyrosine kinase 2; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B]
Gene, Accession #[TrkB], Gene ID: 4915, NCBI: AAB33109.1
Catalog #MBS4152715
Price$515
Order / More InfoTyrosine Kinase Receptor B (TrkB, 23-36) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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