Rat CD11b/c, Low Endotoxin Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Rat CD11b/c, Low Endotoxin |
| Clone | OX-42 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) Frozen/Paraffin, Functional Studies, In Vivo |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD11b/c (pan macrophage). The anti-rat CD11b/c monoclonal antibody recognizes most macrophages including resident peritoneal macrophages, kupffer cells, but only approximately 35% of alveolar macrophages (2). It also labels dendritic cells extensively, granulocytes and cells with morphology of microglia in the brain. It precipitates three polypeptides of M.W. 160, 103 and 95kDa. OX-42 inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for iC3b called CR3. The anti-rat CD11b/c mAb should prove useful in the recognition of macrophages and microglia. This clone is reported to work with frozen and paraffin sections (3); in vivo and in vitro functional tests (4, 5, 6); and cryostat section |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD11b/c] |
| Catalog # | MBS520874 |
| Price | $385 |
| Order / More Info | Rat CD11b/c, Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Aihara, N. et al. (1995) J. Neurotrauma. 12:53-63. 2) Robinson, A.P. et al. (1986) Immunology. 57:239-247. 3) Whiteland J.L. et al. (1995) J. Histochem and Cytochem. 43:313-320. 4) Issekutz, A. C. and T.B. Issekutz, (1992) Immunology. 76:655-661. 5) Yamazaki, T. et al. (1993) Am. J. of Pathology. 143:410-418. 6) Tamatani, T. et al. (1991) Eur. J. Immunol. 21:627-633. 7) Joan Y. et al. (2009) Am J Physiol Regul Integr Comp Physiol. 297:R1532-R1545. 8) Zheng Gen Piao et al. (2005) Pain. 121:219-231. 9) Abbadie C. et al. (2003) PNAS. 100:7947-7952. 10) Lee. et al. (2010) Molecular Pain. 6:79. 11) Summy-Long, J.Y. et al. (2008) Journal of Neuroendocrinology. 20:1224-1232. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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