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Antigenic Specificity | LRP6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 3.9mg/ml |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have n |
Immunogen | Immunogen: Synthetic peptide of human LRP6 Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3 |
Other Names | [ADCAD2] |
Gene, Accession # | [LRP6], Gene ID: 4040 |
Catalog # | MBS2542753 |
Price | $110, $150, $225 |
Order / More Info | LRP6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |