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Antigenic Specificity | HGK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: HGK Polyclonal Antibody detects endogenous levels of HGK protein. Mitogen-activated protein kinase kinase kinase kinase 4 encoded by MAP4K4 is a member of the serine/threonine protein kinase family. Mitogen-activated protein kinase kinase kinase kinase 4 has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human HGK at AA range: 380-460 |
Other Names | [Rabbit HGK; MAP4K4; HGK; KIAA0687; NIK; Mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase] |
Gene, Accession # | [HGK], Gene ID: 9448, NCBI: NP_001229488.1, UniProt: O95819 |
Catalog # | MBS9702215 |
Price | $130, $220, $325 |
Order / More Info | HGK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |