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Antigenic Specificity | AKAP13 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | 0.8 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AKAP13 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 18-170 amino acids from human AKAP13. Anchors cAMP-dependent protein kinase (PKA) and acts as an adapter protein to selectively couple G alpha-13 and Rho. Augments gene activation by the estrogen receptor in an element- specific and ligand-dependent manner. Activates estrogen receptor beta by a p38 MAPK-dependent pathway. Stimulates exchange activity on Rho proteins in vitro, but not on CDC42, Ras or Rac and may bind calcium ions. |
Immunogen | n/a |
Other Names | [A-kinase anchor protein 13; AKAP-13; AKAP-Lbc; Breast cancer nuclear receptor-binding auxiliary protein; Guanine nucleotide exchange factor Lbc; Human thyroid-anchoring protein 31; Lymphoid blast crisis oncogene; LBC oncogene; Non-oncogenic Rho GTPase-specific GTP exchange factor; Protein kinase A-anchoring protein 13; PRKA13; p47; AKAP13; BRX; HT31; LBC; Purified Mouse (Mab)] |
Gene, Accession # | [AKAP13], Gene ID: 11214, NCBI: Q12802.2, UniProt: Q12802 |
Catalog # | MBS9217319 |
Price | $165, $370 |
Order / More Info | AKAP13 Antibody from MYBIOSOURCE INC. |
Product Specific References | Klussmann E.,et al.FEBS Lett. 507:264-268(2001). Diviani D.,et al.J. Biol. Chem. 276:44247-44257(2001). Miyamoto M.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. Rubino D.,et al.Oncogene 16:2513-2526(1998). Sterpetti P.,et al.Mol. Cell. Biol. 19:1334-1345(1999). |