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Antigenic Specificity | Amyloid precursor protein (APP) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amyloid precursor protein (APP), with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms. Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients. |
Immunogen | Immunogen: Ni-NTA purified truncated recombinant APP expressed in E Coli strain BL21 (DE3) |
Other Names | n/a |
Gene, Accession # | [APP] |
Catalog # | MBS418364 |
Price | $445 |
Order / More Info | Amyloid precursor protein (APP) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Yuzhi Chen, Wenyun Liu, Donna L, et al. J. Cell Biol., Oct 2003; 163: 27. 2.Robert Spoelgen, Christine A. F. von Arnim, et al. J. Neurosci., Jan 2006; 26: 418 - 428. |