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Antigenic Specificity | SLC12A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven. |
Immunogen | Immunogen: A synthetic peptide of human SLC12A1 Immunogen Species: Human |
Other Names | [BSC1; NKCC2] |
Gene, Accession # | [SLC12A1], Gene ID: 6557, NCBI: NP_000329.2, UniProt: Q13621 |
Catalog # | MBS9133050 |
Price | $200, $275, $430 |
Order / More Info | SLC12A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |