BPTF Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBPTF
Clonepolyclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionBPTF (bromodomain and PHD domain transcription factor) is the largest subunit of the ATP-dependent chromatin-remodelling complex, NURF (nucleosome remodelling factor). NURF catalyses ATP-dependent nucleosome sliding and facilitates transcription. BPTF recognises histone H3 tails that are tri-methylated at K4, which marks the transcriptional start site of the vast majority of transcriptionally active genes. BPTF also exhibits some binding to H3 di-methylated at K4. BPTF plays a key role in the development of early mouse embryos, possibly through regulation of the Smad pathway of transcription factors. While BPTF is expressed in low levels in the adult brain and spinal cord, it is expressed in higher levels in the brain in neurodegenerative d
ImmunogenImmunogen: Purified recombinant fragment (503-670aa) of human BPTF expressed in E. Coli.
Other Names[FAC1; FALZ; NURF301; BPTF], [BPTF; BPTF; FAC1; FALZ; NEDDFL; NURF301; FAC1; FALZ]
Gene, Accession #[BPTF], Gene ID: 2186, NCBI: NP_004450.3, UniProt: Q12830
Catalog #MBS850263
Price$280
Order / More InfoBPTF Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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