Edit |   |
---|---|
Antigenic Specificity | E2F1 (Phospho-Thr433) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of E2F1 only when phosphorylated at Threonine 433. Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Threonine 433 |
Other Names | [E2F-1, PBR3, RBAP-1, RBBP-3] |
Gene, Accession # | [E2F1], Gene ID: 1869, NCBI: NP_005216.1, UniProt: Q01094 |
Catalog # | MBS9414143 |
Price | $200, $255 |
Order / More Info | E2F1 (Phospho-Thr433) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |