Mouse CD103 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD103 |
| Clone | [2E7] |
| Host Species | Armenian Hamster |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The CD103/ alpha IEL beta 7 integrin complex (Mr 160 and 115 kDa peptides). CD103 is a member of the integrin series of adhesion molecules. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20% of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs, appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis and periphery.1-3 In non-epithelial CD103+ T cells there is a bias toward expression on CD8+.cells. The 2E7 mAb exhibits antigen immunoprecipitation patterns similar if not identical to the rat anti-mouse CD103 mAb M290.1 The 2E7 mAb is reported to have signal-inducing activity in a |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673585 |
| Price | $325 |
| Order / More Info | Mouse CD103 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. LeFrancois, L., T.A. Bennett, W.L. Havran, and L. Puddington. 1994. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. Eur. J. Immunol. 24:635.2. Lefrancois, L. 1991. Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal repertoire? Immunol. Today, 12(12):436.3. Reimann, J. and Rudolphi, A. 1995. Co-expression of CD8 alpha in CD4 T cell receptor alpha beta T cell migration into the murine small intestine epithelial layer. Eur. J. Immunol. 25:1580.4. Roberts, K., and P. Kilshaw. 1993. The mucosal T cell integrin alpha M290 beta 7 recognizes a ligand on mucosal epithelial cell lines. Eur. J. Immunol. 23:1630.5. Cerf-Bensussan, N., Bengue, B., Gagnon, J. and Meo, T. 1992. Eur. J. Immunol. 22:273. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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