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Antigenic Specificity | MIP-1 alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MIP-1 alpha antibody detects endogenous levels of total MIP-1 alpha. Function: Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).Subunit Structure: Self-associates. Also heterodimer of MIP-1-alpha(4-69) and MIP-1-beta(3-69).Post-translational Modifications: N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.Similarity: Belongs to the intercrine beta (chemokine CC) family. |
Immunogen | Immunogen: A synthesized peptide derived from human MIP-1 alpha Subcellular Location: Secreted. Tissue Specificity: By TPA or PHA (TPA = 12-O-tetradecanoyl phorbol-13 acetate (tumor promoter); PHA = phytohemagglutinin (T-cell mitogen)). Predicted Cross Reactivity: Bovine, Horse Similarity: Bovine (100%), Horse (86%) |
Other Names | [C C motif chemokine 3; CCL 3; CCL3; CCL3_HUMAN; Chemokine C C motif ligand 3; G0/G1 switch regulatory protein 19 1; G0/G1 switch regulatory protein 19-1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein; L2G25B; LD78 alpha; LD78-alpha(4-69); LD78alpha; Macrophage inflammatory protein 1 alpha; Macrophage inflammatory protein 1-alpha; MIP 1 alpha; MIP 1A; MIP-1-alpha; MIP-1-alpha(4-69); PAT 464.1; SCYA 3; SCYA3; SIS alpha; SIS beta; SIS-beta; Small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); Small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein] |
Gene, Accession # | [MIP1A], Gene ID: 6348, NCBI: NP_002974.1, UniProt: P10147 |
Catalog # | MBS9608889 |
Price | $240, $280 |
Order / More Info | MIP-1 alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |