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Antigenic Specificity | CRCP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF-Kappa-B through the RIG-I pathway. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human CRCP (NP 001035737.1). |
Other Names | [RCP; RCP9; RPC9; CGRPRCP; CGRP-RCP] |
Gene, Accession # | [CRCP], Gene ID: 27297, NCBI: O75575.1, UniProt: O75575 |
Catalog # | MBS8549540 |
Price | $280 |
Order / More Info | CRCP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |