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Antigenic Specificity | ARL6IP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.6 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ARL6IP1 protein. ARMER (apoptotic regulator in the membrane of the endoplasmic reticulum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a multi-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regulated during myeloid differentiation. ARMER ma |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human ADP-ribosylation factor-like 6 interacting protein 1 |
Other Names | [AIP1; ARMER; ARL6IP] |
Gene, Accession # | [ARL6IP1], Gene ID: 23204, NCBI: NP_055976.1, UniProt: Q15041 |
Catalog # | MBS9403906 |
Price | $255 |
Order / More Info | ARL6IP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |