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Antigenic Specificity | Phospho-ZAP70-Y319 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y319 of human ZAP70 Calculated Molecular Weight: 70kDa |
Other Names | [Phospho-ZAP70-Y319: SRK; STD; TZK; STCD; ZAP-70], [ZAP70; ZAP70; SRK; STD; TZK; STCD; ZAP-70; SRK] |
Gene, Accession # | [ZAP70], Gene ID: 7535, NCBI: P43403.1, UniProt: P43403 |
Catalog # | MBS128571 |
Price | $235, $350, $525 |
Order / More Info | Phospho-ZAP70-Y319 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |