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Antigenic Specificity | AKT1S1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AKT1S1 antibody is human, mouse and rat reactive. At least three isoforms of AKT1S1 are known to exist. AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia (1). AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy (2). Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S |
Immunogen | Immunogen: AKT1S1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1. Buffer: AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [AKT1S1; Lobe; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate; AKT1 substrate 1 (proline-rich)], [AKT1S1; AKT1S1; Lobe; PRAS40] |
Gene, Accession # | [AKT1S1], Gene ID: 84335, NCBI: NP_115751, UniProt: Q96B36 |
Catalog # | MBS153593 |
Price | $375 |
Order / More Info | AKT1S1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |