Edit |   |
---|---|
Antigenic Specificity | TNFRSF1A - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | guinea pig, human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TNFRSF1A. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TNFRSF1A is the receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. TNFRSF1A contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.The protein encoded by this gene is a member of the TNF-receptor superfamily. This pr |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF1A |
Other Names | [tumor necrosis factor receptor superfamily member 1A isoform 1; Tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily member 1A; TNF receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60] |
Gene, Accession # | [TNFRSF1A], Gene ID: 7132, NCBI: NP_001056, UniProt: P19438 |
Catalog # | MBS3224325 |
Price | $365 |
Order / More Info | TNFRSF1A - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |